
What is vis-OCT?
Optical coherence tomography (OCT) has transformed clinical eye care, ocular drug development, and fundamental ophthalmology and vision research since it was reported in 1991.
Visible-light optical coherence tomography (vis-OCT) is the latest development of OCT, providing new capabilities in anatomical and functional imaging of biological tissue. It was first reported by Prof. Hao F. Zhang's group at Northwestern University in 2013 in small animals and has been extended for human use since 2015.
Unlike most commercial and investigational OCTs that use near-infrared light, vis-OCT relies on visible light illumination. This requires different engineering design considerations but brings unique benefits to both fundamental research and clinical care of leading blinding diseases.
Our development of vis-OCT has enabled the creation of our flagship Blizzard spectrometer, which powers the ultra high resolution of many of our systems - as pictured.
FUNCTIONAL IMAGING
New Functional Imaging of the Retina
Thanks to the improved optical contract in the visible-light spectral range, our technology offers new functional analyses of the retina like no other.
SMALL ANIMALS
Revolutionary Small Animal Imaging
Our systems provide the best functional and anatomical ocular imaging of both anterior and posterior segments of small animal eyes.
RETINA
Highest Resolution Retinal Imaging
Our technology is capable of a 1.3 micrometer axial resolution in the human eye, nearly 3x higher than current state-of-the-art clinical OCTs.


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RESEARCH
Enabling Advanced Research
Our vis-OCT systems are currently being evaluated through IRB-approved research studies at major institutions worldwide. The unprecedented resolution and functional imaging capabilities are helping researchers better understand the mechanisms of blinding diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, and optic neuropathy. These insights are accelerating the development of new approaches and methods of recognizing disease.


IMAGING
The Power of Blizzard SR
We've designed the Blizzard SR to have the best-in-class performance, featuring a far superior roll-off performance, high signal-to-noise, and an ideal point spread function.
Research with the Blizzard SR has a much improved resolution of anatomical structures and improved homogeneity of spectra quality over varying depths.
