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We Are Revolutionizing Eye Imaging

Opticent Health develops visible-light optical coherence tomography technologies, which offer the highest spatial resolution and imaging contrast in the market, for clinical, preclinical, and metrology applications

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Halo 375 is the first commercially available visible-light OCT (vis-OCT) system and the most powerful small animal research OCT system to date.

A new perspective has been authored and published by the Opticent Health team in the trade journal, Biophotonics.

Opticent Health research collaboration reveals subtle changes in retina IPL layer related to glaucoma

Milestone Research

High-Speed Balanced-Detection Visible-Light Optical Coherence Tomography in the Human Retina Using Subpixel Spectrometer Calibration

Jan 2022 | IEEE Transactions on Medical Imaging

Impact: First demonstration to reject relative intensity noise in visible-light optical coherence tomography for high-speed clinical imaging.

In vivo sublayer analysis of human retinal inner plexiform layer obtained by visible-light optical coherence tomography

Jan 2022 | Investigative Ophthalmology & Visual Science

Impact: First demonstration to measure the synaptic dropout in retinal ganglion cells in glaucoma patients.

Global and regional damages in retinal ganglion cell axon bundles monitored non-invasively by visible-light optical coherence tomography fibergraphy

Dec 2021 | Journal of Neuroscience

Impact: First demonstration to quantify retinal ganglion axon bundles damages based on label-free imaging.

Visible-light optical coherence tomography fibergraphy for quantitative imaging of retinal ganglion cell axon bundles

Oct 2020 | Translational Vision Science & Technology

Impact: First demonstration to quantify retinal ganglion axon bundle noninvasively in vivo.

In vivo imaging of Schlemm’s canal and limbal vascular network in mouse using visible-light OCT

Feb 2020 | Investigative ophthalmology & visual science

Impact: First demonstration to image the entire outflow pathway in small animals.

Speckle reduction in visible-light optical coherence tomography using scan modulation

Oct 2019 | Bioinformatics

Impact: A new easy-to-implement, motion insensitive method to suppress speckle in human eyes.

Spectroscopic Doppler analysis for visible-light optical coherence tomography

Oct 2017 | Journal of Biomedical Optics

Impact: A new retinal blood flow measurement based on split-spectrum spectroscopic analysis.

Retinal oximetry in humans using visible-light optical coherence tomography

Mar 2017 | Biomedical Optics Express

Impact: First demonstration of the feasibility to measure retinal oxygen saturation in humans using visible-light optical coherence tomography.

Increased inner retinal oxygen metabolism precedes microvascular alterations in rodent model with Type 1 diabetic mice

Feb 2017 | Investigative Ophthalmology & Vision Science

Impact: First investigation to validate retinal ischemia before anatomical alterations in small animal models of diabetic retinopathy.

Optical detection of early damages in retinal ganglion cells in a mouse model of partial optic nerve crush injury

Oct 2016 | Investigative Ophthalmology & Vision Science

Impact: First demonstration of ultra-high sensitivity provided by visible-light optical coherence tomography to sense nanoscopic damages in retinal neurons.

Human retinal imaging using visible-light optical coherence tomography guided by scanning laser ophthalmoscopy

Oct 2015 | Biomedical Optics Express 

Impact: First report of human retinal imaging using visible-light optical coherence tomography.

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation

Sep 2015 | Biomedical Optics Express 

Impact: First report of dynamic changes in retinal oxygen saturations in small animals.

Latest Research

The visible-light optical coherence tomography fibergram

Apr 2020 | Optical Coherence Tomography

Advanced image processing for visible-light OCT oximetry in rodents

Jul 2019 | Investigative Ophthalmology & Visual Science

Speckle Noise Reduction in Visible-Light OCT

Jul 2019 | Optical Coherence Tomography

Relating Vis-OCT Measurements of Retinal SO2 to Microelectrode Measurements of PO2

Jul 2019 | Investigative Ophthalmology & Visual Science

Intra- and Inter-Subject Variability of Retinal Oximetry on Healthy Eyes Using Visible-Light OCT

Jul 2019 | Investigative Ophthalmology & Visual Science

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